Morning Light Treatment for Traumatic Stress: The Role of Amygdala Reactivity

 IRB Registration Number(s): IRB00000244

This is a study evaluating the association between increasing duration of morning light treatment and the degree of change in amygdala reactivity to an emotional faces fMRI task in individuals with a history of traumatic stress. Participants will be randomized to receive 15/30/60-minutes per day of morning light treatment. Amygdala reactivity (via fMRI) and mood and traumatic stress symptoms will be assessed at baseline, after 2 weeks of treatment and after 4 weeks of treatment. In total, participants will be in the study for approximately 5 weeks: a week of baseline plus 4 weeks of treatment. Participants will be monitored via weekly visits for protocol adherence and treatment side effects.

The University of Michigan
Principal Investigator
Alyson K. Zalta
Eligibility Criteria

Inclusion Criteria:

  • Meets criteria for traumatic stress
  • Normal or corrected to normal vision
  • Right-handed
  • Fluency in English
  • Physically able to travel for study visit attendance
Exclusion Criteria

Exclusion Criteria:

  • Significant chronic uncontrolled disease (e.g. uncontrolled diabetes, advanced liver disease, cancer, etc.)
  • Severe hearing problem
  • Intellectual disability or serious cognitive impairment
  • Inability to tolerate enclosed spaces (e.g. the MRI machine)
  • Ferrous-containing metals within the body
  • Pregnant, trying to get pregnant, or breastfeeding
  • Epilepsy
  • Other research participation
  • Frequent number of special events during study period (weddings, concerts, exams, etc.)
The University of Michigan; Ann Arbor, Michigan, United States, 48109
Study End Date