Many women have feelings of depression, sadness, anxiety, and tiredness after childbirth. But, how do you know when it is more than just the baby blues? Postpartum depression is a serious mental health condition that can affect women after they give birth. It does not happen to all women but it is common, with about 10% to 15% of new moms experiencing some type of postpartum depression. These feelings can start right after you give birth or up to several months after you have your baby.